ACIDO USNICO PDF

Validation of a UV-spectrophotometric analytical method for the determination of usnic acid in liposomes. Espectrofotometria no ultravioleta. The secondary lichen metabolite usnic acid [2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-1,3 2H,9bH -dibenzofuran] has demonstrated pharmacological potential activities such as antitumor, antimicrobial, antiviral, antiproliferative, and anti-inflammatory. Liposomes are vesicles composed of phospholipid bilayers surrounding aqueous compartments and they have been used as colloidal drug carriers. The aim of this study was to develop and validate a quantitative UV spectrophotometric method for determination of usnic acid in liposomal formulations.

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Validation of a UV-spectrophotometric analytical method for the determination of usnic acid in liposomes. Espectrofotometria no ultravioleta. The secondary lichen metabolite usnic acid [2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-1,3 2H,9bH -dibenzofuran] has demonstrated pharmacological potential activities such as antitumor, antimicrobial, antiviral, antiproliferative, and anti-inflammatory.

Liposomes are vesicles composed of phospholipid bilayers surrounding aqueous compartments and they have been used as colloidal drug carriers. The aim of this study was to develop and validate a quantitative UV spectrophotometric method for determination of usnic acid in liposomal formulations. The repeatability relative standard deviation of the method was 1. The accuracy revealed a mean percentage recovery of The method was robust for the variation of temperature and solvent.

The detection and quantization limits were found to be 0. The content of usnic acid in liposomes was of The proposed method is accurate, precise and reproducible for estimation of usnic acid as raw material and in pharmaceutical dosage forms such as liposomes. Ultraviolet Spectrophotometry.

Louis, EUA. Os ensaios de doseamento foram realizados em triplicata. Onde, D. Antiperspirant and deodorant compositions containing a low molecular weight polyethylene gellant.

US Patente No. A review on usnic acid, an interesting natural compound. Naturwissenschaften , Berlin, v. Multi-portion antiperspirant composition. Patente No. Composition containing usnic acid or its derivatives for the therapeutical control of dental caries, particularly for the treatment of the cariogenic dental plaque. Usnic acid revisited, its activity on oral flora. Chemioterapia: Int. Usnic acid, a selective antimicrobial agent against Streptococcus mutans : a pilot clinical study.

Methods of manufacturing personal care products. US Patente, No. Encyclopedia of chemical, drugs and biologicals. New Jersey: Merck, ICH Q2 R1. Validation of Analytical Procedures: Text and Methodology.

Acesso em: 20 mar. Antimycobacterial activity of lichen metabolites in vitro. JI, X. Quantitative determination of usnic acid in usnea lichen and its products by reversed-phase liquid chromatography with photodiode array detector. AOAC Int. Liposomes : From physics to application. Amsterdam: Elsevier, Agents Chemother. NEFF, G. Severe hepatotoxicity associated with the use of weight loss diet supplements containing ma huang or usnic acid.

Development and validation of a new HPLC analytical method for the determination of alprazolam in tablets. In vitro and in vivo properties of usnic acid encapsulated into PLGA-microspheres.

Usnic acid-loaded nanocapsules: an evaluation of cytotoxicity. Drug Del. Spectroscopic and structural characterization of copper II and palladium II complexes of a lichen substance: usnic acid and its derivatives. Possible forms of environmental metals retained in lichens. Rockville: United States Pharmacopoeial Convention, High-performance liquid chromatographic determination of usnic acid in plasma. All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License.

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Acido usnico

Gli estratti dei licheni contenenti acido usnico sono stati utilizzati in medicina, profumeria, in ambito cosmetico ed altri campi ancora. Si tratta di un potente antibiotico efficace contro i batteri Gram-positivi, inclusi Staphylococcus , Streptococcus ed altri batteri come il Mycobacterium tuberculosis. Agisce anche contro alcuni funghi patogeni. L'acido usnico viene utilizzato come ingrediente di creme, polveri, dentifrici, collutori, deodoranti, shampoo per capelli e prodotti per la protezione solare. In alcuni di questi preparati, la molecola viene impiegata come principio attivo, in altri come conservante.

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