In vitro diagnosis of acute lymphoid leukemias. The initial diagnosis approach consists of a peripheral blood and bone marrow cytomorphological examination. The cytogenetic techniques have markedly contributed to the better understanding of molecular biology and ALL treatment. Chromosomal abnormalities, associated with the immunophenotyping panel, are the most important parameter for leukemia classification. Together with clinical and in vitro factors, this parameter allows the patients stratification in different risk groups, which is of great importance for establishing a prognosis and a suitable treatment.
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In vitro diagnosis of acute lymphoid leukemias. The initial diagnosis approach consists of a peripheral blood and bone marrow cytomorphological examination. The cytogenetic techniques have markedly contributed to the better understanding of molecular biology and ALL treatment.
Chromosomal abnormalities, associated with the immunophenotyping panel, are the most important parameter for leukemia classification. Together with clinical and in vitro factors, this parameter allows the patients stratification in different risk groups, which is of great importance for establishing a prognosis and a suitable treatment. The aim of this study was to perform a bibliographic review of the laboratory methods by morphological, cytochemical, immune, cytogenetic and molecular genetic patterns, which are useful tools for acute lymphoid leukemia classification and diagnosis.
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Leucemia Linfocitica Aguda
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Estadísticas importantes sobre la leucemia linfocítica aguda (ALL)